Figure 1. The dose and strain dependent effects of probiotics on HF diet-induced obesity, insulin resistance and hepatic steatosis.
WT C57BL/6 mice were fed either ND or HF diet and some of HF fed mice were also treated with high dose VSL#3 (HF+hi VSL#3), or low dose VSL#3 (HF+lo VSL#3), or antibiotics (HF+anti) or high dose of B. infantis (HF+hi B infantis), or continue ND or HF diet. (A) Animal weight; (B) Glucose tolerance tests; (C) serum insulin level; (D) Insulin resistance measured by HOMA-IR; (E) Hepatic triglyceride content; (F) Representative H&E of liver histology. * p<0.05 vs HF diet group.