Figure 4. Disrupting TLR4 signaling did not protect mice from HF diet-induced NAFLD.
Wild type and TLR4 knock out C57BL6 mice were fed ND or HF diet for 12 weeks. (A) Hepatic NKT cell content; (B) Animal weight; (C) Glucose tolerance tests; (D) Insulin resistance as measured by HOMA-IR; (E) Representative H&E staining of liver histology; (F) Hepatic triglyceride content. Results were means ± SD (n=5 per group)