Table 1. Summary of IL-6-type cytokines and their receptor complexes.
Cytokine | Receptor complex subunits | ||
---|---|---|---|
α-receptor | β-receptor | No. of gp130 involved in an induced receptor/ligand complex | |
IL-6 | IL-6R | - | 2 |
IL-11 | IL-11R | - | 2 |
IL-27 | IL-27R | - | 2 |
LIF | - | LIFR | 1 |
CNTF | CNTFR | LIFR | 1 |
CT-1 | ? | LIFR | 1 |
OSM | - | LIFR or OSMR | 1 |
CLC-1 | CNTFR | LIFR | 1 |