Figure 3. Immunogenicity of hgB vaccines.
Guinea pigs were immunized with two doses of either hgB (no adjuvant), hgB/AS01E or hgB/AS01B one month apart. Geometric mean anti-hgB antibody concentrations (GMCs) (A) and human CMV neutralizing titers (GMTs) (B) in the immunogenicity cohort of Study 2. Immunogenicity was measured in samples taken at, (A) 28 days post 1st immunization (28dPI); and (A and B) 14 days post 2nd immunization (14dPII). Error bars describe 95% confidence intervals (95% CIs).