TABLE 2.

Alignment of the six amino acid residues within the catalytic fold of Uge3, hGalE, tGalE, and WbpP shows highest alignment between Uge3 and hGalE

Six amino acid residues in the catalytic pocket were identified on the Uge3 model. These residues were then compared with those in hGalE, tGalE, and WbpP. Visualization was performed using MacPyMOL Version 1.3.

Species	Enzyme	Residues						Group
A. fumigatus	Uge3	Lys151	Ser191	Tyr238	Asn268	Asn288	Cys391	2
H. sapiens	hGalE	Lys92	Ser132	Tyr157	Asn187	Asn206	Cys307	2
T. brucei	tGalE	Leu102	Ser142	Tyr173	Asn202	His202	Leu342	1
P. aeruginosa	WbpP	Gly102	Ser142	Tyr166	Asn195	Ala209	Ser306	3