TABLE 2.

Thermodynamic parameters for ligand binding to STM2200 and its variants in 20 mm MES-NaOH, 0.025% (w/v) β-DDM, 150 mm NaCl, pH 5.9 at 20 °C

^a Stoichiometric coefficient.

^b K_a, association constant.

^c K_d, dissociation constant; K_d = 1/K_a.

^d Details are given under “Experimental Procedures” and “Results.”