TNFα (10 ng/ml) increases K+ current in tsA-201 cells transfected with wild-type hTASK3.
a, traces of current obtained using the voltage protocol (see “Experimental Procedures”) on cells treated for 1, 2, and 15 h with TNFα (10 ng/ml) compared with untreated cells. b, histogram of current density (mean ± S.E. (error bars)) in control cells and cells incubated with TNFα at different times: 1, 2, and 15 h (unpaired t test; *, p ≤ 0.05; **, p ≤ 0.01). c, current-voltage plot of hTASK3 current density in untreated tsA-201 cells (control) or cells treated with TNFα 10 ng/ml, 2-h incubation, and transfected with hTASK3 gene.