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. 2013 Dec 4;289(3):1388–1401. doi: 10.1074/jbc.M113.500033

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FIGURE 5. — TNFα (10 ng/ml) has no effect on K⁺ current at an external acidic pH of 6.4 in tsA-201 cells transfected with wild-type hTASK3. a, traces of current obtained using the voltage protocol on cells incubated in an external solution of pH 6.4 treated with TNFα (10 ng/ml) compared with untreated cells. b, current-voltage plot of hTASK3 current density in tsA-201 cells untreated or treated with TNFα for 2 h and incubated in an external solution of pH 6.4. c, histogram of current density (mean ± S.E. (error bars)) in control cells and cells treated with TNFα at an external pH of 6.4 or 7.4 (one-way ANOVA; *, p ≤ 0.05; NS, p > 0.5). Significant inhibition of current induced by pH 6.4 is compared with pH 7.4 for control and TNFα-treated cells (one-way ANOVA; +, p ≤ 0.05; ++, p ≤ 0.01).