FIGURE 2.

Overall structure of the Ssh10b-RNA complex and interactions between Ssh10b and the RNA. A, ribbon diagrams of the Ssh10b-RNA complex and that rotated by 90° about the vertical axis. The four Ssh10b monomers are colored in green, magenta, yellow, and blue, respectively. The secondary structural elements of monomer A are labeled. Two complementary RNA strands are colored in orange and white, respectively. B, electron density of the RNA in the Ssh10b-RNA complex. C, a schematic diagram summarizing the Ssh10b-RNA interactions. All hydrogen bonds between Ssh10b and the 25-bp dsRNA are shown as dashed lines. D, E, and F, close-up views of the interfaces between the RNA and molecule A, B, or D. Interacting residues and nucleotides are shown as sticks and labeled. Hydrogen bonds are shown as dashed lines. mol, molecule.