FIGURE 2.

Patterns of amino acid substitutions present in the ATII-LCL MerA relative to the soil ortholog. A, amino acid compositions of the ATII-LCL and soil enzymes were compared, and the plot shows the net change in the number of each of the listed amino acids in the ATII-LCL enzyme. B, frequency of substitutions in ATII-LCL plotted against corresponding residue in the soil enzyme. C, patterns of gain, loss, and net change of amino acids in ATII-LCL relative to the soil enzyme based on their functional classifications.