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Model of angiotensin I binding to C-domain ACE. The structure of the C-domain ACE·Ang complex (Protein Data Bank code 4APH (36)) was used to model Angiotensin I before catalysis. The AngI peptide is represented in gray, chloride is shown in green, zinc ion is shown in gray, and water molecules are shown in red. The potential hydrogen bonds are shown in dashed lines. Residue 522 is presented in a stick representation.
