Table 4.

Six-week efficacy study: changes in vital signs from baseline to post-baseline time-points.

Parameter	MPP	Comparator	Group x Time P-value
SBP, Week 3 (mmHg)			0.076
Mean (SD)	3.2 (6.6)	-0.8 (7.2)
Within Group P-value	0.033	0.654
SBP, Week 6 (mmHg)			0.323
Mean (SD)	-2.2 (7.4)	0.7 (10.7)
Within Group P-value	0.191	0.777
DBP, Week 3 (mmHg)			0.161
Mean (SD)	0.6 (6.6)	-2.2 (5.4)
Within Group P-value	0.677	0.107
DBP, Week 6 (mmHg)			0.011
Mean (SD)	-1.7 (6.9)	6.9 (12.8)
Within Group P-value	0.267	0.035
HR, Week 6 (bpm)			0.709
Mean (SD)	2.5 (6.9)	1.5 (9.3)
Within Group P-value	0.116	0.502

Student's t test.