Table 2.
Genotype and allele distributions in tumorous tissue and adjacent normal tissue of HCC patients treated by LT
| SNP | Adjacent normal tissues n (%) | tumorous tissues n (%) | P value | Recurrence-free n (%) | Recurrence n (%) | P value | Survival n (%) | Death n (%) | P value |
|---|---|---|---|---|---|---|---|---|---|
| rs1990172 | |||||||||
| GG | 83(72.2) | 135(75.8) | 0.310a | 52(85.3) | 61(68.5) | 0.001c | 54(80.6) | 59(71.1) | 0.072c |
| GT | 31(27.0) | 38(21.4) | 6(9.8) | 26(29.2) | 10(14.9) | 22(26.5) | |||
| TT | 1(0.8) | 5(2.8) | 3(4.9) | 2(2.3) | 3(4.5) | 2(2.4) | |||
| G allele | 197(85.7) | 308(86.5) | 0.807b | ||||||
| T allele | 33(14.3) | 48(13.5) | |||||||
| rs3735615 | |||||||||
| GG | 86(73.5) | 140(76.5) | 0.394a | 50(80.7) | 63(69.2) | 0.179c | 54(79.4) | 59(69.4) | 0.255c |
| CG | 31(26.5) | 41(22.4) | 11(17.7) | 27(29.7) | 13(19.1) | 25(29.4) | |||
| CC | 0(0.0) | 2(1.1) | 1(1.6) | 1(1.1) | 1(1.5) | 1(1.2) | |||
| G allele | 203(86.8) | 321(87.7) | 0.801b | ||||||
| C allele | 31(13.2) | 45(12.3) | |||||||
| rs4721888 | |||||||||
| GG | 75(64.1) | 119(65.0) | 0.932a | 38(61.3) | 61(67.0) | 0.741c | 44(64.7) | 55(64.7) | 0.610c |
| CG | 33(28.2) | 52(28.4) | 19(30.6) | 24(26.4) | 20(29.4) | 23(27.1) | |||
| CC | 9(7.7) | 12(6.6) | 5(8.1) | 6(6.6) | 4(5.9) | 7(8.2) | |||
| G allele | 183(78.2) | 290(79.2) | 0.760b | ||||||
| C allele | 51(21.8) | 76(20.8) | |||||||
| rs2241056 | |||||||||
| GG | 60(51.3) | 95(51.9) | 0.567a | 32(51.6) | 50(54.9) | 0.543c | 36(52.9) | 46(54.1) | 0.921c |
| AG | 53(45.3) | 77(42.1) | 25(40.3) | 38(41.8) | 29(42.7) | 34(40.0) | |||
| AA | 4(3.4) | 11(6.0) | 5(8.1) | 3(3.3) | 3(4.4) | 5(5.9) | |||
| G allele | 173(73.9) | 267(73.0) | 0.850b | ||||||
| A allele | 61(26.1) | 99(27.0) | |||||||
| rs975263 | |||||||||
| TT | 82(70.1) | 129(72.9) | 0.363a | 49(80.3) | 58(65.2) | 0.004c | 51(76.1) | 56(67.5) | 0.087c |
| CT | 34(29.1) | 43(24.3) | 8(13.1) | 30(33.7) | 12(17.9) | 26(31.3) | |||
| CC | 1(0.8) | 5(2.8) | 4(6.6) | 1(1.1) | 4(6.0) | 1(1.2) | |||
| T allele | 198(84.6) | 301(85.0) | 0.907b | ||||||
| C allele | 36(15.4) | 53(15.0) |
aχ2 test. (Pearson χ2 test). bχ2 test. (Fisher's exact test). cLog-rank test.