Table 4.

Multivariate Cox regression analysis of variables related to tumor recurrence at univariate analysis

Model	variable	HR(95% CI)	P value
rs1990172
Dominant	GT&TT genotype	1.80(1.14-2.85)	0.011
	Tumor size>5cm	2.46(1.58-3.83)	<0.001
	AFP >400 ng/mL	1.83(1.17-2.88)	0.009
	PVTT	2.44(1.59-3.75)	<0.001
Overdominant	GT genotype	2.27(1.41-3.66)	0.001
	Tumor size>5cm	2.30(1.47-3.61)	<0.001
	AFP >400 ng/mL	1.95(1.24-3.07)	0.004
	PVTT	2.50(1.62-3.85)	<0.001
rs975263
Dominant	CT&CC genotype	1.69(1.09-2.63)	0.02
	Tumor size>5cm	2.58(1.65-4.03)	<0.001
	AFP >400 ng/mL	1.83(1.16-2.88)	0.01
	PVTT	2.36(1.54-3.63)	<0.001
Overdominant	CT genotype	2.16(1.37-3.39)	0.001
	Tumor size>5cm	2.49(1.59-3.90)	<0.001
	AFP >400 ng/mL	1.94(1.23-3.07)	0.004
	PVTT	2.41(1.56-3.72)	<0.001

AFP, α-fetoprotein; PVTT, portal vein tumor thrombi; HR, hazard ratio; CI, confidence interval.