Table 1.
PEP activity in CRC tissue according to clinicopathologic characteristics. Values are means ± SE of peptidase activity recorded as pmol of units of peptidase (UP) per milligram of protein.
| Variables | n = | UP/mg prot (Media ± S.E ) | T student (p =) |
|---|---|---|---|
| Grade | |||
| Low (G1-G2) | 62 | 14337 ± 1062 | 0.284 |
| High (G3-G4) | 18 | 11776± 1914 | |
| Stage | |||
| Low (T1-T2) | 11 | 12282 ± 1963 | 0.721 |
| High (T3-T4) | 69 | 13964 ± 1026 | |
| Nodal invasion | |||
| No | 49 | 14825 ± 1311 | 0.213 |
| Yes | 31 | 12442 ± 1269 | |
| Distant Metastases | |||
| No | 73 | 13651 ± 988 | 0.527 |
| Yes | 7 | 15680 ± 3062 | |
| Lymphatic invasion | |||
| No | 71 | 14058 ± 1012 | 0.531 |
| Yes | 9 | 12146 ± 2820 | |
| Vascular invasion | |||
| No | 65 | 14983 ± 1058 | 0.014 |
| Yes | 15 | 9134 ± 1685 | |
| Perineural invasion | |||
| No | 75 | 14013 ± 962 | 0.461 |
| Yes | 5 | 10952 ± 4314 | |
| Grouped stage | |||
| Low (0-IIC) | 45 | 14605 ± 1372 | 0.389 |
| High (IIIA-IV) | 35 | 12975 ± 1255 |