Figure 7.
Loss of Draper delays neurite degeneration and clearance of vCrz+ neuronal cell bodies. (A) vCrz+ neurons were labeled with GFP (Crz-Gal4, UAS-mCD8∷GFP; green). Time points are as indicated (APF). Bars, 20 μm. Genotypes used were as follows: control (Crz-Gal4, UAS-mCD8∷GFP; +), drprΔ5/+ (Crz-Gal4, UAS-mCD8∷GFP; drprΔ5/+), and drprΔ5 (Crz-Gal4, UAS-mCD8∷GFP; drprΔ5). (B–D) Quantification of the percentage of intact lateral (B), medial (C), and horizontal (D) axons of vCrz+ neurons per hemisegment from A. (B–E) Control, N = 30; drprΔ5/+, N = 30; and drprΔ5, N = 32 hemisegments quantified. Error bars represent ±SEM. (*) P < 0.05; (***) P < 0.001; (****) P < 0.0001. (E) Quantification of the percentage of cell bodies of vCrz+ neurons per hemisegment from A.