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. 2014 Jan 1;28(1):71–84. doi: 10.1101/gad.231050.113

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© 2014 Youngren et al.; Published by Cold Spring Harbor Laboratory Press

This article, published in Genes & Development, is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 3. — Replicated loci separate in three limited zones where the replication forks are active. (A) Replication forks show narrow distributions centered around either the cell center or the cell quarters. Their long axis distributions match well with the distribution of duplicated loci in the action of separation inferred by the elongated shape of the splitting foci. (B) The position and dynamics of the replication forks are likely the consequence of the spatial organization of the chromosomes rather than vice versa (see the text).