Table 1.
Electrophysiological properties of V3 spinal INs
| Electrophysiological properties | Cluster 1 (N = 65) | Cluster 2 (N = 57) | p value |
|---|---|---|---|
| Input R (MΩ) | 233.092 ± 132.088 | 1038.522 ± 648.563 | <0.001 |
| Cm (pF) | 66.477 ± 15.770 | 29.263 ± 9.768 | <0.001 |
| Resting membrane potential (mV) | −44.778 ± 2.576 | −47.123 ± 3.374 | <0.001 |
| f–I slope (average spike frequency) | 0.172 ± 0.0737 | 0.827 ± 0.293 | <0.001 |
| f–I slope (1st spike) | 1.639 ± 1.686 | 1.502 ± 1.127 | 0.047 |
| 10 HZ 1st spike latency (s) | 0.0189 ± 0.00992 | 0.0484 ± 0.0197 | <0.001 |
| 10 HZ 1st spike frequency (Hz) | 53.195 ± 34.406 | 18.878 ± 14.393 | <0.001 |
| 10 HZ Spike frequency adaptation | 7.525 ± 6.459 | 1.437 ± 0.700 | <0.001 |
| Rheobase (pA) | 38.672 ± 21.710 | 8.745 ± 6.654 | <0.001 |
| 1st spike latency (s) | 0.204 ± 0.435 | 0.348 ± 0.198 | <0.001 |
| 1st spike amplitude (mV) | 93.258 ± 9.791 | 87.565 ± 11.286 | 0.004 |
| 1st spike absolute amplitude | 37.865 ± 10.829 | 28.732 ± 10.590 | <0.001 |
| 1st spike threshold (mV) | −41.337 ± 4.609 | −39.763 ± 4.625 | n.s. |
| 1st spike width (ms) | 0.969 ± 0.230 | 0.915 ± 0.225 | n.s. |
| 80 pA spike number | 8.063 ± 6.060 | 38.688 ± 11.126 | <0.001 |
| 10 HZ afterstimulus hyperpolarization | 6.372 ± 2.661 | 2.402 ± 1.173 | <0.001 |
| Sag amplitude at −120 mV (mV) | 26.137 ± 6.572 | 12.865 ± 4.549 | <0.001 |
| Sag membrane potential slope | −0.437 ± 0.132 | −0.217 ± 0.0801 | <0.001 |
| Latency of rebound spike at −120 mV (s) | 0.0285 ± 0.0333 | 0.114 ± 0.0610 | <0.001 |
| Latency of 1st rebound spike (s) | 0.0845 ± 0.0524 | 0.272 ± 0.341 | <0.001 |
| Membrane potential of 1st rebound spike (mV) | −82.541 ± 9.220 | −96.602 ± 14.987 | <0.001 |
Data are given as the mean ± SD.