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Targets of HOCl at a site of inflammation and its interaction with taurine. Inside phagolysosomes, HOCl kills ingested microbes. Outside phagolysosomes, taurine neutralizes detrimental effects of HOCl on neighboring cells and protects “self” molecules from oxidative modification. TauCl, the product of this reaction, is less toxic than HOCl. TauCl is not membrane permeable, oxidizes distinct targets and causes less damage to biologically active molecules (Marcinkiewicz and Kontny 2012)
