Fig. 10. Model depicting the Polβ/XRCC1 interaction.
Structure of a complex formed by the thumb sub-domain of Polβ and the N-terminal domain of XRCC1 [132]. The image is a spacefilling rendition of the amino acid residues of XRCC1 in green and the thumb sub-domain of Polβ in red. The residues in the V303 hairpin, corresponding to L301, V303 and V306 are shown in yellow. The image was generated using PyMOL (Molecular Graphics System, Version 1.2r3pre; Schrödinger, LLC; http://pymol.org/).