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. 2014 Jan 17;4:3754. doi: 10.1038/srep03754

Figure 4. Analysis of insulin and glucose contents in the brain and plasma of fasting huApoE TR mice.

Figure 4

(A) Lower brain glucose was detected in E4 TR (grey bar) mice at 32 and 72 weeks of age as compared to E3 TR mice (white bar) of similar age. But higher brain insulin was only detected in 72 weeks old E4 TR mice (dotted line) as compared to E3 TR mice (bold line) at similar age. (B) No significant change in plasma insulin and glucose contents between E3 TR and E4 TR mice at 32 and 72 weeks of age. Each value represents the mean ± SEM of duplicate assays for individual samples (n = 5). (*p < 0.04; ** p < 0.001; *** p < 0.004, using Student's t-test).