Table 4. Clinical profile of patients with echocardiographically assessed moderate or severe pulmonary hypertension according to history of invasive hemodynamic monitoring by right heart catheterization (RHC).
| Characteristic | RHC (N=122) | Non-RHC (N=218) | P-Value |
|---|---|---|---|
|
| |||
| Comorbidities | |||
| Total | 15.5 (7.0) | 12.9 (5.3) | <0.001 |
| Cardiovascular | 5.5 (2.9) | 4.9 (2.6) | <0.01 |
| Pulmonary | 1.4 (1.4) | 1.2 (1.3) | 0.07 |
| Echocardiography | |||
| LV Ejection Fraction | .47 (.17) | .51 (.16) | <0.03 |
| LA Size (cm) | 4.6 (0.8) | 4.3 (0.7) | <0.01 |
| IVS (cm) | 1.2 (0.6) | 1.1 (0.2) | 0.81 |
| LV EDD (cm) | 5.2 (0.8) | 4.9 (0.9) | <0.01 |
| TR Velocity (cm/s) | 3.85 (0.38) | 3.73 (0.38) | <0.02 |
| RA Pressure (mmHg) | 12.3 (5.3) | 11.5 (5.2) | 0.15 |
| PASP (mmHg) | 72.0 (12.4) | 67.5 (9.8) | <0.002 |
| Pulmonary Function Test | |||
| FEV-1/FVC (%) | 75.0 (15.1) | 76.3 (16.8) | 0.81 |
| FEV-1 (%) | 61.5 (20.7) | 64.9 (24.1) | 0.32 |
| FVC (%) | 71.2 (20.2) | 68.5 (18.0) | 0.71 |
| DLCO (%) | 48.3 (16.7) | 49.4 (22.0) | 0.76 |
For Pulmonary Function Test data, results are expressed as percent of predicted. LV, left ventricle; LA, left atrium; IVS, intraventricular septum; EDD, end-diastolic dimension; TR tricuspid valve regurgitation; RA, right atrium; FEV-1, forced expiratory volume in one second; FVC, forced vital capacity; DLCO, diffusion lung capacity for carbon monoxide, PASP, pulmonary artery systolic pressure; mPAP, mean pulmonary artery pressure.