Table 4.

Comparison of Fish/Shellfish^* Consumption (Servings/Week) High in Omega-3 Fatty Acids between Controls and Categories of Age-Related Macular Degeneration

	Cases/No. at Risk	<1 Serving/Week	1+ Servings/ Week OR (95% CI)
AMD1†
Crude	327/3041	Ref	0.9 (0.7–1.3)
Age-adjusted	327/3041	Ref	0.9 (0.6–1.2)
Adjusted‡	327/3030	Ref	0.9 (0.6–1.3)
AMD2*
Crude	188/2902	Ref	1.0 (0.6–1.5)
Age-adjusted	188/2902	Ref	0.9 (0.6–1.4)
Adjusted‡	186/2889	Ref	1.0 (0.6–1.6)
AMD3†
Crude	102/2816	Ref	0.4 (0.2–0.8)
Age-adjusted	102/2816	Ref	0.3 (0.1–0.7)
Adjusted‡	100/2803	Ref	0.4 (0.2–0.8)

AMD = age-related macular degeneration; CI = confidence interval; OR = odds ratio.

^*High omega-3 fatty acid weekly fish/shellfish = crab +oysters +fried fish + “other fish”.

^†Control eyes = those eyes without AMD disease (not classified as AMD1, AMD2, AMD3, or missing or ungradable photos in both eyes); AMD1 = drusen ≥125 µm and not classified as AMD2 or AMD3; AMD2 = pigment abnormalities and not classified as AMD3 (AMD3); (AMD3) = geographic atrophy or neovascular AMD.

^‡Adjusted for gender (male or female), age (years), race (black or white), smoking status (current, former, or never) and correlation between eyes using multiple logistic regression analyses.