Table 5.

Comparison of Fish/Shellfish Consumption (Servings/Week) High in Zinc^* between Controls and Categories of Age-Related Macular Degeneration

	Cases/No. at Risk	<0.07 Servings/Week	0.07 + Servings/Week OR (95% CI)
AMD1†
Crude	327/3043	Ref	0.9 (0.7–1.2)
Age adjusted	327/3043	Ref	0.9 (0.7–1.2)
Adjusted‡	327/3032	Ref	0.9 (0.7–1.2)
AMD2†
Crude	188/2904	Ref	1.2 (0.8–1.6)
Age adjusted	188/2904	Ref	1.2 (0.8–1.7)
Adjusted‡	186/2891	Ref	1.2 (0.8–1.6)
AMD3†
Crude	102/2818	Ref	1.1 (0.7–1.9)
Age adjusted	102/2818	Ref	1.1 (0.7–1.9)
Adjusted‡	100/2805	Ref	1.0 (0.6–1.7)

AMD = age-related macular degeneration; CI = confidence interval; OR = odds ratio.

^*High zinc = crab + oysters.

^†Control eyes = those eyes without AMD disease (not classified as AMD1, AMD2, AMD3, or missing or ungradable photos in both eyes); AMD1 = drusen ≥125 µm and not classified as AMD2 or AMD3; AMD2 = pigment abnormalities and not classified as AMD3 (AMD3); (AMD3) = geographic atrophy or neovascular AMD.

^‡Adjusted for gender (male or female), age (years), race (black or white), smoking status (current, former, or never), and correlation between eyes using multiple logistic regression analyses.