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Pooled estimator from combining the UMLYNCH and DLYNCH estimators for genetic anticipation (from Table A.1 – not adjusted for within-family correlation); the method for pooling used was that prescribed by DerSimonian and Laird [1986] for combining estimates across studies with different sample sizes, using the inverse variances as weights.
| n | t-test | HV | RY1 | RY2 | |
|---|---|---|---|---|---|
| UMLYNCH | 136 | 7.42*** | 3.11** | 0 | 3.05* |
| DLYNCH | 290 | 9.84*** | 4.73*** | 2.97* | 5.39*** |
| POOLED | 426 | 12.29*** | 5.64*** | 1.39 | 3.79*** |
