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[3H]Clozapine, [3H]quetiapine, [3H]remoxipride, and [3H]amisulpride quickly dissociated or were quickly displaced from human-cloned D2 receptors upon the rapid addition of 100 μM raclopride in vitro. In contrast, [3H]olanzapine, [3H]haloperidol, [3H]raclopride, and [3H]chlorpromazine were displaced much more slowly from the D2 receptors. (Adapted from ref (26).)
