Figure 3.

An oral dose of 350 mg occupied 72% of human striatal D2 receptors at 2 h, with the occupation falling to less than 30% at 24 h. The occupation of human D2 dropped even faster with oral quetiapine (400 mg). Oral haloperidol (7.5 mg) occupied high levels of D2 for at least 27 h.^26,40