Figure 6. Noggin attenuates the activated BMP signaling in pancreatitis.
Pancreatic tissue samples were obtained from the groups described in Figure 3. The pancreas from the mice treated with PBS alone was included as a baseline control. Protein lysates were prepared for Western blotting analysis using specific antibodies against pSmad1/5/8. β-actin served as a protein loading control. A. Western blotting images. B. Quantification of the corresponding Western blots. The protein levels were normalized against β-actin and quantified. The data are expressed as relative fold changes to PBS group. n=6–7 mice in CR or N+CR group. * p<0.05 compared N+CR to CR.