Table 2.
Summary of results for ADR collagen lattice contraction
| Released on Day 4 |
Genistein | Vanadate | ML-7 | Y-27632 |
|---|---|---|---|---|
| Myofibroblasts 10–15 minutes |
No effect 1.1 4E-4L |
Less contraction 1.5 4E-4L |
No effect 1.0 1E-4L |
No effect 1.7 1E-3L |
| Myofibroblasts 5 hours |
No effect 1.2 4E-4L |
Less contraction 1.6 4E-4L |
No effect 1.0 1E-4L |
Much less contraction 4.2 1E-3L |
| SMC 10 –15 minutes |
No effect 1.1 2E-4L |
No effect 1.1 2E-4L |
No effect 1.2 2E-4L |
Less contraction 1.2 2E-4L |
| SMC 5 hours | No effect 1.1 2E-4L |
No effect 0.94 2E-4L |
No effect 1.2 2E-4L |
No effect 1.2 2E-4L |
| No Treatment Release Day 1 | No Treatment Release Day 4 | |||
| Fibroblasts | contracted 11% | contracted 52% | ||
| SMC | contracted −0.03% NS | contracted 6% | ||
No effect or NS indicates not statistically significant. The single number in the top part of the table is the ratio of the average treated lattice area over the control. The 4E-4L indicates 4 experiments with 4 lattices in each experiment. The results given for 1 experiment are consistent with results when the experiment was repeated two more times.