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. Author manuscript; available in PMC: 2014 Jan 17.
Published in final edited form as: Cell Rep. 2013 Nov 7;5(3):738–747. doi: 10.1016/j.celrep.2013.10.001

Figure 3. Higher levels of amplitude of BOLD oscillations are associated with functional brain hyper-connectivity in children with ASD.

Figure 3

(a) fMRI timeseries averaged across all gray-matter voxels in the brain from a representative child with ASD (blue) and a TD child (red), illustrating abnormally high amplitude fluctuations in children with ASD. (b) Mean amplitude of fMRI BOLD oscillations (ALFF) was greater in ASD than TD (p < 0.05, d′ = 0.68). (C) Higher regional ALFF was associated with higher levels of whole-brain connectivity in children with ASD (r = 0.54, p = 0.01). * p < 0.05. Error bars represent standard error of mean. See also Figure S3, S6.