Fig. 1.
Amoebic liver abscess formation in the hamster model of hepatic amoebiasis Male Syrian golden hamsters (Mesocricetus auratus) were infected intraportally with virulent parasites (8×105 trophozoites per animal) according to our published protocol [7]. Livers were excised and fixed immediately after necropsy at 24 hours post-inoculation (A). Shown is a paraffin-embedded section of infected liver stained with hematoxylin to visualize the mammalian cells (in blue) and immuno-labelled with a human anti-E. histolytica antibody (in pink). Note the presence of massive infiltrates containing inflammatory cells. Over time, the inflammatory foci coalesce and form macroscopic abscesses (B). Scale bar, 100 μm