Table 1. Genes Downregulated in the Lungs of PBS-treated DDAH1-transgenic Mice versus PBS-treated Wild Type Mice.
| Symbol | Name | Fold Change |
| Immune/Defense Response | ||
| Rag1 | recombination activating gene 1 | 0.0020 |
| Irg1 | immunoresponsive gene 1 | 0.0042 |
| Tlr6 | toll-like receptor 6 | 0.0224 |
| Saa3 | serum amyloid A 3 | 0.0265 |
| Clec4e | C-type lectin domain family 4, member e | 0.0360 |
| Ptafr | platelet-activating factor receptor | 0.0656 |
| Pram1 | PML-RAR alpha-regulated adaptor molecule 1 | 0.1024 |
| Clec4d | C-type lectin domain family 4, member d | 0.1306 |
| Cfd | complement factor D (adipsin) | 0.1491 |
| Cd4 | CD4 antigen | 0.2667 |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.3327 |
| Il1rn | interleukin 1 receptor antagonist | 0.3365 |
| Lilrb3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.3596 |
| Sell | selectin, lymphocyte | 0.3826 |
| Acsl1 | acyl-CoA synthetase long-chain family member 1 | 0.4620 |
| Cybb | cytochrome b-245, beta polypeptide | 0.4694 |
| Lcn2 | lipocalin 2 | 0.4804 |
| Tgtp1 | T-cell specific GTPase 1 | 0.4907 |
| Lilrb4 | leukocyte immunoglobulin-like receptor, subfamily B, member 4 | 0.4931 |
| Tgtp2 | T-cell specific GTPase 2 | 0.4986 |
| Csf2rb | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.5378 |
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.6052 |
| Cell Structure/Adhesion/Migration | ||
| Sprr2a2 | small proline-rich protein 2A2 | 0.0179 |
| Sprr2a1 | small proline-rich protein 2A1 | 0.0179 |
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.0702 |
| S100a9 | S100 calcium binding protein A9 (calgranulin B) | 0.0736 |
| Pla2g7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.1651 |
| S100a8 | S100 calcium binding protein A8 (calgranulin A) | 0.2070 |
| H2-M2 | histocompatibility 2, M region locus 2 | 0.2210 |
| Sema4d | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.2948 |
| Itgb2 | integrin beta 2 | 0.4746 |
| Myh6 | myosin, heavy polypeptide 6, cardiac muscle, alpha | 0.4752 |
| Itgal | integrin alpha L | 0.4913 |
| Actc1 | actin, alpha, cardiac muscle 1 | 0.5662 |
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.5942 |
| Cytokine/Chemokine | ||
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.0000 |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.0114 |
| Cxcl2 | chemokine (C-X-C motif) ligand 2 | 0.0236 |
| Il1b | interleukin 1 beta | 0.1342 |
| Transcriptional Factor | ||
| Tcf7 | transcription factor 7, T-cell specific | 0.4134 |
| Stat1 | signal transducer and activator of transcription 1 | 0.5833 |
| Other | ||
| Arpp21 | cyclic AMP-regulated phosphoprotein, 21 | 0.0036 |
| Gxylt2 | glucoside xylosyltransferase 2 | 0.0112 |
| 1700071M16Rik | RIKEN cDNA 1700071M16 gene | 0.0427 |
| Trim30b | tripartite motif-containing 30B | 0.0516 |
| Cd177 | CD177 antigen | 0.0746 |
| Niacr1 | niacin receptor 1 | 0.0993 |
| Mmp8 | matrix metallopeptidase 8 | 0.1307 |
| Slfn4 | schlafen 4 | 0.1469 |
| Acpp | acid phosphatase, prostate | 0.2390 |
| Steap4 | STEAP family member 4 | 0.2412 |
| F13a1 | coagulation factor XIII, A1 subunit | 0.2631 |
| Gpnmb | glycoprotein (transmembrane) nmb | 0.3398 |
| Slpi | secretory leukocyte peptidase inhibitor | 0.3547 |
| Bpifa1 | BPI fold containing family A, member 1 | 0.3796 |
| Gp49a | glycoprotein 49 A | 0.4032 |
| Car3 | carbonic anhydrase 3 | 0.4062 |
| Gm1966 | predicted gene 1966 | 0.5319 |
| Ctss | cathepsin S | 0.6001 |
| Fth1 | ferritin heavy chain 1 | 0.6449 |
NCBI Gene Expression Omnibus accession numbers GSE49047 (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE49047).