Table 2. Genes Upregulated in the Lungs of PBS-treated DDAH1-transgenic Mice versus PBS-treated Wild Type Mice.
Symbol | Name | Fold Change |
Muscle/Cell Structure | ||
Myh2 | myosin, heavy polypeptide 2, skeletal muscle, adult | 181.3505 |
Myh8 | myosin, heavy polypeptide 8, skeletal muscle, perinatal | 109.1566 |
Myh4 | myosin, heavy polypeptide 4, skeletal muscle | 82.8001 |
Myh1 | myosin, heavy polypeptide 1, skeletal muscle, adult | 65.6757 |
Tnnt3 | troponin T3, skeletal, fast | 44.0881 |
Actn3 | actinin alpha 3 | 26.0940 |
Mylpf | myosin light chain, phosphorylatable, fast skeletal muscle | 14.9051 |
Neb | nebulin | 10.4391 |
Ion Homeostasis/Metabolism | ||
Atp2a1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 45.0004 |
Ckm | creatine kinase, muscle | 9.6517 |
Sod1 | superoxide dismutase 1, soluble | 1.8226 |
Errfi1 | ERBB receptor feedback inhibitor 1 | 1.7924 |
Dpep1 | dipeptidase 1 (renal) | 1.6845 |
Sgms1 | sphingomyelin synthase 1 | 1.6440 |
Glul | glutamate-ammonia ligase (glutamine synthetase) | 1.4929 |
Hemopoiesis | ||
Hba-a2 | hemoglobin alpha, adult chain 2 | 1.6691 |
Hba-a1 | hemoglobin alpha, adult chain 1 | 1.6691 |
Beta-s | hemoglobin subunit beta-1-like | 1.5436 |
Hbb-b1 | hemoglobin, beta adult major chain | 1.5242 |
Hbb-b2 | hemoglobin, beta adult minor chain | 1.5242 |
MicroRNA | ||
Mir5109 | microRNA 5109 | 2.7839 |
Other | ||
Flrt2 | fibronectin leucine rich transmembrane protein 2 | 11.5849 |
Gm13375 | predicted gene 13375 | 8.1901 |
Gm3893 | predicted gene 3893 | 5.6492 |
Rmrp | RNA component of mitochondrial RNAase P | 4.8670 |
Angptl4 | angiopoietin-like 4 | 2.7019 |
Efnb1 | ephrin B1 | 2.3349 |
Zbtb16 | zinc finger and BTB domain containing 16 | 2.2658 |
Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 2.2030 |
Tsc22d3 | TSC22 domain family, member 3 | 2.1869 |
6430548M08Rik | RIKEN cDNA 6430548M08 gene | 2.1316 |
Krt7 | keratin 7 | 2.0891 |
Bmp6 | bone morphogenetic protein 6 | 1.8952 |
Gm10393 | predicted gene 10393 | 1.8802 |
Lars2 | leucyl-tRNA synthetase, mitochondrial | 1.8365 |
Plxna2 | plexin A2 | 1.8323 |
Eif3e | eukaryotic translation initiation factor 3, subunit E | 1.7913 |
Cpm | carboxypeptidase M | 1.7450 |
Rn45S | 45S pre-ribosomal RNA | 1.7382 |
Vps54 | vacuolar protein sorting 54 (yeast) | 1.5716 |
Dnaja1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 1.5133 |
Tmbim6 | transmembrane BAX inhibitor motif containing 6 | 1.4524 |
Sepp1 | selenoprotein P, plasma, 1 | 1.3714 |
Sftpa1 | surfactant associated protein A1 | 1.3527 |
NCBI Gene Expression Omnibus accession numbers GSE49047 (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE49047).