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(A) Intermolecular NOEs between RNA and DPQ in the NOESY spectrum. (B) Overlay of 2D NOESYs of the free RNA (black) and complex (red). (C) DPQ interacts with the internal loop and its proximal base pairs. (D) The interaction of (A11-A12)-U23 and DPQ. Dotted lines indicate hydrogen bonds based on close contacts observed in the structure.
