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| Author (year) | Inclusion criteria clearly described | Controlgroup | Standardization of AT-II administration | Standardization of T/N ratio measurement | Blinding for outcome measurement |
| Sasaki et al. [25] | N | N | Y | Y | N |
| (1985) | |||||
| Goldberg et al. 1 [33] | N | N | Y | Y | N |
| (1991) | |||||
| Goldberg et al. 2 [34] | N | N | Y | Y | N |
| (1991) | |||||
| Burke et al. [19] | Y | N | Y | Y | N |
| (2001) | |||||
| Ishikawa et al. [36] | N | N | Y | Y | N |
| (2007) |
Abbreviations: Y = Yes, N = No.
