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. Author manuscript; available in PMC: 2014 Jan 18.
Published in final edited form as: Psychopharmacology (Berl). 2009 Dec 15;208(3):401–416. doi: 10.1007/s00213-009-1740-z

Figure 6. Clozapine ameliorated the PPI deficit in the female mice lacking M1 and M4 receptors, while startle-suppressing effects of high doses were absent in mice lacking M4 or both receptors.

Figure 6

Abscissae: dose clozapine [mg/kg]. Ordinates: Total %PPI (A–C), startle amplitude (D–F). N=9–12. Data are group means, bars represent one s.e.m. *p<0.05, **p<0.01 vs. vehicle, Dunnett's multiple comparisons test; †p<0.05, ††p<0.01 vs. wild-type, Bonferroni-corrected unpaired-sample t-test.