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. Author manuscript; available in PMC: 2014 Jul 7.
Published in final edited form as: Nat Commun. 2014;5:3051. doi: 10.1038/ncomms4051

Figure 1. Effects of calpain inhibitor III on BDNF-induced changes in levels of SCOP and p-ERK.

Figure 1

a, d, g. Experimental protocols: hippocampal slices were prepared from adult rats and were treated with BDNF (100 ng/ml) for the indicated periods of time in the absence or presence of calpain inhibitor III (10 µM), as indicated. b, e, h. Representative western blots for SCOP, Akt, p-ERK and ERK under various experimental conditions. c, f, i. Quantitative analysis of the levels of SCOP (normalized to the values of Akt) and p-ERK/ERK ratios under various experimental conditions. In all cases, results are means ± S.E.M. of 3 experiments. * p < 0.05, as compared to time point 0, one-way ANOVA followed by Bonferroni test.