Table 4.
Fold change in neuroimaging parameters between baseline, day 15, and over 1 y of treatment
| Median Fold Change at Day 15 (range) | P | Median Maximum Fold Change Over 1 Year of Treatment (range) | P | |
|---|---|---|---|---|
| Volume enhancement | 0.69 (0.02, 1.88) (n= 28) | <.0001 | 0.73 (0.15, 1.88) (n = 33) | .037 |
| Volume FLAIR | 0.92 (0.57, 1.23) (n = 27) | .015 | 1.01 (0.57, 3.11) (n = 30) | .426 |
| Kps 3D Max | 0.51 (0.00, 1.53) (n = 12) | .016 | 0.78 (0.00, 10.28) (n = 14) | .903 |
| CBV 3D Max | 0.86 (0.00, 3.27) (n = 12) | .457 | 1.00 (0.00, 3.27) (n = 14) | .761 |
| Diffusion ratio | 0.94 (0.58, 1.47) (n = 30) | .156 | 1.06 (0.70, 2.22) (n = 33) | .111 |
| T/GM ratio* | 0.83 (0.68, 2.00) (n = 9) | .250 | – | – |
| T/WM ratio* | 0.83 (0.56, 1.23) (n = 9) | .164 | – | – |
P values are based on Wilcoxon signed-rank tests.
*Based on baseline and one on treatment scan.