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. Author manuscript; available in PMC: 2014 Apr 24.
Published in final edited form as: Nature. 2013 Oct 6;502(7472):513–518. doi: 10.1038/nature12602

Figure 2. Mode of ORS growth.

Figure 2

a) In vivo lineage tracing sequence (top) and corresponding 3D renderings of the Cre reporter (bottom) showing ORS expansion during hair growth. Arrows denote different lineages. b) Graphical representation of the location and axis of cell divisions in the ORS and Matrix (Bulb) in advanced hair follicle growth (Anagen III-IV). c) ORS cell distribution during active hair growth. d) Quantification of cell density in different regions of the outer hair follicle epithelial layer (n = 9 per region; error bars represent S.E.M.). e) Individual traces of migrating ORS nuclei (see also Video S1). f) Traces of ORS nuclei depicting their relative positions at two time-points eight hours apart (see also Video S3). Scale bars: 50μm.