Table 2.

Carotid Intima-Media Thickness and Biomarkers in Human Immunodeficiency Virus (HIV)–Infected Patients and Healthy Controls Subjects

	Median value (range)
Measurement	HIV-infected patients (n = 73)	Control subjects (n = 21)	P
ICA IMT, mm	1.35 (0.7–3.88)	1.10 (0.55–2.98)	.04
CCA IMT, mm	1.25 (0.75–3.23)	1.05 (0.75–1.35)	<.001
TNF-α, pg/mL	4.0 (0.4–364)	1.8 (0.4–85.6)	.03
sTNFR-I, pg/mL	702 (161–17, 328)	618 (265–1365)	.09
sTNFR-II, pg/mL	518 (100–3073)	635 (279–1070)	.89
hsCRP, mg/L	5.43 (0.13–84.6)	1.53 (0.05–24.4)	<.001
IL-6, pg/mL	6.0 (0.8–270)	2.8 (1.0–8.2)	.008
MPO, pg/mL	7665 (1022–32,439)	1561 (1124–10,865)	<.001
sICAM-1, ng/mL	401 (73–2818)	403 (195–577)	.25
sVCAM-1, ng/mL	659 (239–17,145)	454 (66–1808)	.002
vWF, U/mL	17.0 (2.0–3121)	11.8 (6.4–200)	.11

NOTE. CCA, common carotid artery; hsCRP high sensitivity C-reactive protein; ICA , internal carotid artery; IL, interleukin; IMT, intima-media thickness; MPO, myeloperoxidase; sICAM-1, soluble intercellular adhesion molecule-1; sTNFR-I , soluble tumor necrosis factor–α receptor I; sTNFR-II, soluble tumor necrosis factor–α receptor II; sVCAM-1, soluble vascular cell adhesion molecule-1; TNF-α, tumor necrosis factor–α; vWF, von Willebrand factor.