Table 3.

Significant Univariable Correlations between Carotid Intima-Media Thickness and Biomarkers for HIV-Infected Patients and Healthy Control Subjects

	HIV-infected patients (n = 73)				Control subjects (n = 21)
Marker	CCA IMTa	P	ICA IMTa	P	CCA IMTa	P	ICA IMTa	P
Age	0.54	.001	0.47	.001	0.66	.001	0.53	.01
Non-HDL cholesterol	0.27	.02	0.25	.04	...		...
Triglycerides	0.25	.03	...		0.6	.004	...
HOMA-IR score	0.24	.04	...		...		0.44	.05
hsCRP	...		0.26	.03	0.47	.03	...
sVCAM-1	...		...		...		–0.70	<.001

NOTE. No significant correlations were found between IMT and biomarkers not listed in the table (ie, TNF-α, sTNFR-I, sTNFR-II, IL-6, MPO, sICAM-1, and vWF), as well as between IMT and TC, HDL, LDL, or BMI. BMI, body mass index (calculated as weight in kilograms divided by the square of height in meters); CCA, common carotid artery; HDL, high-density lipoprotein; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; ICA, internal carotid artery; IL, interleukin; IMT, intima-media thickness; LDL, low-density lipoprotein; MPO, myeloperoxidase; sICAM-1, soluble intercellular adhesion molecule-1; sTNFR-I, soluble tumor necrosis factor-α receptor I; sTNFR-II, soluble tumor necrosis factor-α receptor II; sVCAM-1, soluble vascular cell adhesion molecule-1; TC, total cholesterol; TNF-α, tumor necrosis factor-α; vWF, von Willebrand factor.

^aSpearman correlation coefficient (ρ).