Table 3. Comparison of the designs of the 1000 Genomes and Genome of the Netherlands projects.
1000G | GoNL | |
---|---|---|
Source of DNA | Cell lines | Blood |
Coverage | 3–4 × | >12 × |
Data generation | Multiple centers/ platforms | BGI (Illumina HiSeq) |
Population | Unrelated and multiple populations | One population (Dutch) and trio/twin design |
Phenotype information | None | Multiple, prospective |