Table 2.
Expression of p-MET and its correlation with clinicopathological parameters in 121 cases
| Parameters | Grouping | n |
p-MET [case (%)] |
χ
2
test |
||
|---|---|---|---|---|---|---|
| Positive | Negative | χ 2 value | P value | |||
|
Age (year) |
<60 |
40 |
24(60.0) |
16(40.0) |
0.766 |
0.862 |
| ≥60 |
81 |
48(59.3) |
33(40.7) |
|
|
|
|
Gender |
Male |
77 |
48(62.3) |
29(37.7) |
1.976 |
0.187 |
| Female |
44 |
24(54.5) |
20(45.5) |
|
|
|
|
Tumor diameter (cm) |
<5 |
48 |
33(68.8) |
15(31.3) |
1.138 |
0.236 |
| ≥5 |
73 |
39(53.4) |
34(46.6) |
|
|
|
|
Location of tumor |
Cardia, fundus |
20 |
15(75.0) |
5(25.0) |
10.252 |
0.009 |
| Body |
37 |
27(73.0) |
10(27.0) |
|
|
|
| Pylorus, antrum |
64 |
30(46.9) |
34(53.1) |
|
|
|
|
Lauren classification |
Intestinal |
84 |
55(65.5) |
29(34.5) |
0.924 |
0.186 |
| Diffuse |
37 |
17(45.9) |
20(54.1) |
|
|
|
|
Histological type |
Grade 1 |
25 |
13(52.0) |
12(48.0) |
0.192 |
0.741 |
| Grade 2 |
47 |
28(59.6) |
19(40.4) |
|
|
|
| Grade 3 |
49 |
31(63.3) |
18(36.7) |
|
|
|
|
Invasion depth |
T1 |
18 |
9(50.0) |
9(50.0) |
1.996 |
0.156 |
| T2 |
32 |
18(56.3) |
14(43.8) |
|
|
|
| T3 |
30 |
19(63.3) |
11(36.7) |
|
|
|
| T4 |
41 |
26(63.4) |
15(36.6) |
|
|
|
|
Metastatic lymph node ratio |
<35% |
60 |
30(50.0) |
30(50.0) |
8.556 |
0.007 |
| ≥35% |
61 |
42(68.9) |
19(31.1) |
|
|
|
|
Involving lymph node station |
N0 |
43 |
20(46.5) |
23(53.5) |
9.651 |
0.042 |
| N1 |
41 |
27(65.9) |
14(34.1) |
|
|
|
| N2 |
26 |
16(61.5) |
10(38.5) |
|
|
|
| N3 |
11 |
9(81.8) |
2(18.2) |
|
|
|
|
TNM stages |
Ia |
16 |
8(50.0) |
8(50.0) |
10.887 |
0.016 |
| Ib |
17 |
8(47.1) |
9(52.9) |
|
|
|
| II |
20 |
13(65.0) |
7(35.0) |
|
|
|
| IIIa |
20 |
13(65.0) |
7(35.0) |
|
|
|
| IIIb |
22 |
14(63.6) |
8(36.4) |
|
|
|
| IV |
26 |
16(61.5) |
10/38.5) |
|
|
|
| Survival (month) | <20 |
75 |
52(69.3) |
23(30.7) |
10.006 |
0.004 |
| ≥20 | 46 | 20/(43.5) | 26/(56.5) | |||