Table 3.
Synaptic and gap junction parameters for the striatal network.
| Parameter | Value | Source and notes |
|---|---|---|
| Eampa,Enmda | 0 mV | Moyer et al., 2007 |
| Egaba | −60 mV | Moyer et al., 2007 |
| τampa | 6 ms | Moyer et al., 2007 |
| τnmda | 160 ms | Moyer et al., 2007 |
| τgaba | 4 ms | Moyer et al., 2007 |
| τ FSI gap | 5 | Fitted to Galarreta and Hestrin (1999) |
| [Mg2+]0 | 1 mM | Jahr and Stevens, 1990 |
| gampa Ctx-SPN | 0.4 nS | Tuning (see main text) |
| gampa Ctx-FSI | 1 nS | Fits linear rise in EPSC data from Gittis et al. (2010) |
| gnmda Ctx-SPN | 0.2 nS | Fixed by maintaining the 2:1 AMPA:NMDA ratio from Moyer et al. (2007) |
| ggaba SPN-SPN | 0.75 nS | Koos et al., 2004 |
| ggaba FSI-SPN | 3.75 nS | Mean 5-fold increase compared to SPN-SPN (Koos et al., 2004); 3× increase of PSP (Planert et al., 2010) |
| ggaba FSI-FSI | 1.1 nS | Gittis et al., 2010 |
| g FSI gap | 5 nS | Fitted to Galarreta and Hestrin (1999) |
| β1 | 0.5 | Tuning (see main text) |
| β2 | 0.3 | Tuning (see main text) |