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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Cancer Immunol Res. 2013 Aug;1:99–111. doi: 10.1158/2326-6066.CIR-13-0047

Figure 7.

Figure 7

TRP1 TN cells migrating to the tumor show an exhausted phenotype. A) RAG2−/− mice were inoculated with 100,000 B16 cells one day prior to transfer of naïve CD8+ T cells from TRP1high or TRP1low TN mice. Tumor volume was measured over time. **p=0.001. Representative of 3 independent experiments. B) End stage tumors from mice in A) were harvested, digested with collagenase and tumor infiltrating lymphocytes were analyzed by flow cytometry after staining with the indicated antibodies. n=5 mice per group.