Table 7.

Voxelwise analysis: Significant and Reliable Functional Connectivity

Seed ROI	BA	X	Y	Z	Z-Score	Multi-Scan		Inter-Session		Intra-Session
						Mean	Max	Mean	Max	Mean	Max
PCC POSITIVE CONNECTIVITY
L PCC	29/30	6	58	28	12.1	0.65	0.80	0.61	0.82	0.64	0.77
L vmPFC	10/11	6	-54	-4	7.7	0.54	0.64	0.37	0.58	0.65	0.81
L ITG	21	64	12	−18	7.6	0.69	0.84	0.55	0.82	0.61	0.75
R MFG	11	-4	-38	-18	7.6	0.50	0.68	0.49	0.75	0.43	0.69
L precuneus	19	38	80	36	7.4	0.54	0.67	0.36	0.57	0.41	0.64
L medial PFC	9	8	−48	34	7.3	0.07	0.66	0.22	0.60	0.01	0.69
R medial PFC	9/10	−12	−58	12	6.9	0.55	0.69	0.43	0.67	0.61	0.78
R ITG	21	−62	8	−22	6.8	0.57	0.65	0.50	0.68	0.57	0.74
R MFG	8	−24	−24	44	6.7	0.65	0.79	0.57	0.80	0.67	0.77
R MTG		−48	62	26	6.5	0.79	0.87	0.71	0.86	0.74	0.90
L lingual gyrus	18	10	56	4	6.5	0.48	0.69	0.61	0.77	0.26	0.62
L SFG	6	20	−28	38	6.5	0.64	0.78	0.51	0.77	0.64	0.79
PCC Negative Connectivity
L anterior insula		38	2	−2	−7.3	0.33	0.60	0.25	0.62	0.29	0.56
R anterior insula		−40	−2	−4	−7.2	0.41	0.73	0.42	0.76	0.36	0.73
R precentral gyrus	6	−58	−10	2	−7.2	0.75	0.83	0.71	0.77	0.69	0.78
BL SMA/preSMA		−2	−6	48	−7.0	0.42	0.59	0.39	0.68	0.50	0.78
L IPL		62	30	22	−7.0	0.51	0.73	0.52	0.71	0.41	0.73
R SFG	6	−20	4	62	−7.0	0.07	0.48	0.13	0.40	0.01	0.56
R AG	39	−62	36	34	−6.6	0.57	0.72	0.52	0.75	0.52	0.64
L MOG	19	54	66	−10	−6.6	0.64	0.72	0.42	0.58	0.58	0.66
R IFG	45	−46	−42	6	−6.5	0.62	0.72	0.55	0.68	0.58	0.72
R precentral gyrus	6	−48	0	38	-6.5	0.50	0.68	0.39	0.68	0.45	0.64
L precentral gyrus	6	58	−2	8	−6.4	0.49	0.72	0.36	0.59	0.59	0.73
L MFG	46	38	−40	22	−6.4	0.49	0.65	0.40	0.64	0.53	0.75
SMA Positive Connectivity
BL SMA		2	−10	46	12.2	0.68	0.78	0.58	0.73	0.68	0.83
L anterior insula		32	−20	0	7.4	0.44	0.68	0.33	0.58	0.41	0.58
L SFG	6	16	2	66	6.8	0.56	0.64	0.46	0.56	0.43	0.64
R thalamus		−8	−2	8	6.8	0.44	0.56	0.32	0.50	0.48	0.67
L MFG	46	40	−40	20	6.8	0.22	0.46	0.16	0.42	0.06	0.42
R anterior insula		−34	−22	−2	6.6	0.07	0.65	0.32	0.53	0.01	0.76
L ACC	24	10	−24	24	6.3	0.42	0.73	0.28	0.64	0.39	0.66
R SFG	6	−22	0	62	6.3	0.50	0.65	0.39	0.59	0.57	0.74
L precentral gyrus	6	40	6	46	6.0	0.53	0.73	0.34	0.61	0.57	0.78
R precentral gyrus	6	−44	−4	36	6.0	0.64	0.77	0.57	0.74	0.65	0.78
L IPL		56	42	42	5.9	0.43	0.57	0.19	0.42	0.38	0.64
L caudate/putamen		16	−6	2	5.7	0.25	0.37	0.23	0.61	0.16	0.60
SMA Negative Connectivity
L precuneus	7	4	62	34	−6.9	0.44	0.62	0.42	0.74	0.43	0.54
L cerebellum		22	84	−32	−6.4	0.19	0.29	0.12	0.31	0.14	0.38
L ITG	20	62	10	−20	−5.9	0.46	0.57	0.29	0.52	0.50	0.63
R cerebellum		−20	84	−30	−5.8	0.23	0.37	0.19	0.54	0.30	0.62
L PCC	30	18	56	18	−5.8	0.03	0.38	0.18	0.41	0.04	0.35
BL subgenual  cingulate	25	0	−18	−12	−5.7	0.07	0.42	0.08	0.17	0.01	0.46
R PCC	29	−4	52	12	−5.7	0.45	0.60	0.08	0.39	0.45	0.56
R medial PFC	10	−4	−62	−8	−5.5	0.31	0.48	0.22	0.42	0.37	0.63
R vmPFC	11	−8	−44	−16	−5.5	0.35	0.49	0.07	0.24	0.51	0.65
R PhG		−24	26	−20	−5.4	0.19	0.45	0.01	0.43	0.03	0.40
R STG/AG	39	−54	60	28	−5.2	0.59	0.75	0.47	0.63	0.49	0.71
L PhG		22	24	−18	−5.2	0.16	0.44	0.19	0.43	0.19	0.38
IPS Positive Connectivity
R IPS		−26	58	48	12.3	0.55	0.66	0.31	0.56	0.51	0.66
L IPS		22	78	32	7.9	0.54	0.74	0.34	0.63	0.43	0.63
L IPS		24	66	50	7.2	0.48	0.76	0.30	0.67	0.49	0.75
R precuneus	7	−24	80	38	7.1	0.47	0.72	0.53	0.72	0.32	0.55
R fusiform gyrus	37	−52	60	−16	7.0	0.46	0.65	0.41	0.66	0.32	0.60
L IPS		32	46	44	6.8	0.07	0.75	0.54	0.72	0.01	0.73
R MOG	1	−34	80	16	6.8	0.44	0.64	0.41	0.59	0.32	0.68
L MOG	19	48	70	−10	6.7	0.48	0.63	0.33	0.51	0.40	0.66
L MOG	18/19	34	76	14	6.2	0.40	0.62	0.20	0.55	0.46	0.71
R SFG	6	−22	2	50	6.1	0.33	0.58	0.34	0.70	0.16	0.50
R fusiform gyrus	19	−22	72	−16	6.1	0.49	0.61	0.29	0.56	0.44	0.60
R IPL	40	−40	42	56	6.1	0.15	0.46	0.24	0.54	0.17	0.56
IPS Negative Connectivity
R medial PFC	10	−2	−56	−2	−7.6	0.11	0.41	0.04	0.27	0.02	0.30
BL rostral ACC	32	2	−42	18	−7.5	0.16	0.39	−0.06	0.26	0.28	0.48
L subgenual ACC	32	6	−36	−8	−6.8	0.37	0.52	0.17	0.48	0.28	0.65
L STG/AG	39	52	58	22	−6.3	0.36	0.59	0.23	0.49	0.51	0.82
L ITG	20	56	16	−26	−6.3	0.36	0.54	0.15	0.41	0.37	0.58
L caudate/putamen		−12	−2	−10	−6.2	0.07	0.28	0.13	0.49	0.01	0.35
L SFG	10	20	−60	12	−5.8	0.33	0.49	0.10	0.30	0.35	0.59
L PCC	29/30	6	54	28	−5.8	0.31	0.50	0.15	0.43	0.19	0.45
L precuneus	7	38	80	36	−5.7	0.43	0.60	0.32	0.60	0.32	0.53
L SFG	8	22	−28	44	−5.6	0.54	0.66	0.43	0.64	0.44	0.71
L PhG		30	32	−12	−5.6	0.06	0.33	0.03	0.18	0.24	0.53
R STG/AG	39	−56	60	24	−5.6	0.17	0.52	0.26	0.49	0.18	0.57

Note: Listed are the top twelve peaks of connectivity for the positive and negative networks associated with each seed ROI (PCC, SMA, or Right IPS), the corresponding peak Z score and mean and maximum ICC (computed for a 10mm diameter sphere centered on the corresponding peak voxel). Z score values represent multi-scan functional connectivity calculated from a mixed-effects model subsequent to fixed-effects analysis for each participant combining scans 1, 2, and 3. Abbreviations: ACC, anterior cingulate cortex; AG, angular gyrus; BL, bilateral; IFG, inferior frontal gyrus; IPL, inferior parietal lobule; IPS, intraparietal sulcus; ITG, inferior temporal gyrus; L, left; MFG, middle frontal gyrus; MOG, middle occipital gyrus; PCC, posterior cingulate cortex; PFC, prefrontal cortex; PhG, parahippocampal gyrus; R, right; SFG, superior frontal gyrus; SMA, supplementary motor area; STG, superior temporal gyrus; vmPFC, ventral medial prefrontal cortex.