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Effect of RAGE knockdown on cell proliferation. A) The proliferative activities of gastric cancer SGC-7901 cells were assessed by MTT assay, indicating that knockdown of RAGE significantly diminished the proliferative activities of SGC-7901 cells in a time-dependent manner (**P<0.01). The amount of PCNA, indicated by real-time (B) and Western blot assays (C), was significantly decreased in Lv-shRAGE group compared with that in NC group (**P<0.01).
