Table 1.
Demographic (A) and pre-treatment (B) values in control, neuropathic POTS and hyperadrenergic POTS subjects while supine and during HUT
| (A) | ||||
|---|---|---|---|---|
| Parameter | Controls (n = 14) | Neuropathic POTS (n = 12) | Hyperadrenergic POTS (n = 8) | P values |
| Age (years) | 17.2 ± 0.6 | 16.1 ± 0.5 | 16.8 ± 0.85 | 0.4 |
| Height (m) | 1.68 ± 0.02 | 1.69 ± 0.02 | 1.67 ± 0.04 | 0.8 |
| Weight (kg) | 63.4 ± 2.6 | 65.0 ± 5.0 | 58.0 ± 5.0 | 0.5 |
| BMI (kg/m2) | 23.0 ± 0.9 | 22.7 ± 1.5 | 20.5 ± 1.3 | 0.4 |
| (B) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Controls (n = 14) |
Neuropathic POTS (n = 12) |
Hyperadrenergic POTS (n = 8) |
||||||
| Parameter | Tilt angle... | 0° | 35° | 0° | 35° | 0° | 35° | P values |
| HR (beats/min) | 68 ± 3 | 80 ± 3 | 71 ± 4 | 97 ± 6‡ | 77 ± 5* | 103 ± 9‡ | 0.02, 0.0001 | |
| MAP (mmHg) | 78 ± 2 | 80 ± 2 | 74 ± 3 | 79 ± 3 | 80 ± 3 | 80 ± 4 | 0.6 | |
| Q̇calf (ml/100ml per min) | 3.02 ± 0.4 | 2.42 ± 0.3 | 3.15 ± 0.4 | 3.69 ± 0.9 | 1.06 ± 0.1‡ | 1.69 ± 0.3 | 0.03 | |
| Cv (ml/100ml) | 5.00 ± 0.3 | 4.54 ± 0.3 | 2.99 ± 0.3‡ | 0.0004 | ||||
Values are means ± S.E.M.
*
P < 0.05
† P < 0.01
‡
P < 0.001 between the experimental groups