TABLE 2.

Laboratory findings—variation with PNPLA3 genotype

Variables	PNPLA3 genotyping			P-values— overall
	CC	CG	GG
ALT (IU/l)	30.9 ± 15.1	33.0 ± 16.4	47.3 ± 31.9	0.16
AST (IU/l)	27.2 ± 8.3	26.7 ± 11.2	37.8 ± 15.9	0.02
Cholesterol (mg/dl)	195.0 ± 39.4	186.7 ± 34.7	184.6 ± 33.6	0.60
LDL (mg/dl)	112.9 ± 32.5	108.8 ± 32.3	107.3 ± 32.1	0.81
HDL (mg/dl)	47.4 ± 12.0	48.4 ± 12.0	44.6 ± 10.0	0.80
Triglycerides (mg/dl)	165.0 ± 73.3	155.26 ± 2.7	163.1 ± 70.1	0.85
Glucose (mg/dl)	112.5 ± 35.6	124.0 ± 54.7	153.8 ± 86.9	0.36
Insulin (µIU/ml)	18.3 ± 14.8	19.6 ± 11.4	23.2 ± 14.1	0.20
HOMA-IR	5.2 ± 5.2	6.3 ± 5.0	9.9 ± 9.2	0.09
IL-6 (pg/ml)	5.8 ± 6.7	13.5 ± 30.4	7.1 ± 4.3	0.08
CK-18 (IU/l)	247 ± 137	242 ± 127	225 ± 86	0.96
CRP (mg/dl)	0.96 ± 1.20	1.39 ± 1.93	1.07 ± 0.77	0.49
cC4 (µg/ml)	419 ± 126	401 ± 145	412 ± 65	0.35
Free IGF-1 (ng/ml)	0.94 ± 0.28	0.97 ± 0.30	0.97 ± 0.43	0.75
GH (ng/ml)	0.28 ± 0.35	0.42 ± 0.53	0.56 ± 0.67	0.54
DHEA-S (µg/dl)	97.9 ± 74.0	92.8 ± 86.5	62.4 ± 39.4	0.36
C-peptide (nmol/l)	1.3 ± 0.5	1.4 ± 0.9	1.1 ± 0.6	0.27
Leptin (ng/ml)	47.6 ± 25.1	50.0 ± 24.9	60.3 ± 44.3	0.63
Adiponectin (ng/ml)	8435 ± 3693	8375 ± 3815	8317 ± 3243	0.997
Resistin (ng/ml)	16.3 ± 5.5	17.1 ±8.4	17.0 ± 5.9	0.89
TNF-α (pg/ml)	1.57 ± 0.60	1.58 ± 0.76	1.79 ± 0.68	0.37
Fibrinogen	441 ± 93	468 ± 108	521 ± 104	0.07

Comparison of CC versus non-CC.