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Adult ovarian phenotype is disturbed in the C451A-ERα mice. (A) Representative images of WT-C451 and C451A-ERα ovaries (×25). CL, corpus luteum; HCF, hemorrhagic cystic follicles. (B) Percentages of corpora lutea and hemorrhagic/cystic follicles were determined in ovaries from 3-mo-old WT-C451 and C451A-ERα mice, n = 4. (C) Serum E2, progesterone (PG), FSH, and LH concentrations in 3-mo-old WT-C451 and C451A-ERα mice, n = 9.
